Lectures: 2,005 | Views: 15,975,459 | Subscribers: 126,362 | Subscribe
Phospholipids
The cell membranes of eukaryotic cells and some bacterial cells consist of three types of lipids - phospholipids, glycolipids and cholesterol molecules. Phospholipids generally consists of four types of components - a platform molecule that acts as an attachment point for other groups, one or more fatty acids, a phosphate group and an alcohol group. Phospholipids can be categorized based on the type of platform molecule used to build the lipid. If the platform molecule is a glycerol (a three-carbon alcohol), then the phospholipid is called a phosphoglyceride. On the other hand, if the platform molecule is a sphingosine (a more complex alcohol molecule), then the phospholipid is called a sphingolipid. In phosphoglycerides, the two fatty acids are attached via an ester bond to the C1 and C2 atoms of the glycerol while the phosphate group is attached via an ester bond to the C3 atom of the glycerol. The phosphate group can be modified with alcohols such as choline, ethanolamine, inositol, serine and glycerol. The simplest phosphoglyceride in which the phosphate is not modified is called a phosphatidate. In sphingolipids, a single fatty acid is attached to the nitrogen of the sphingosine via an amide bond while the phosphate group is attached onto the primary alcohol via an ester bond. The phosphate group can also be modified; for instance, in sphingomyelin, the phosphate group is modified with a choline molecule. Phospholipids are amphipathic; they contains both polar regions (phosphate and alcohol group) and nonpolar regions (fatty acids).
[{"id":"32F9xpfXUsc","title":"Properties of Cell Membrane","link":"http:\/\/www.aklectures.com\/lecture\/properties-of-cell-membrane"},{"id":"eB9tgWB4YEw","title":"Fatty Acids","link":"http:\/\/www.aklectures.com\/lecture\/fatty-acids"},{"id":"nqBe9jAlTgQ","title":"Fatty Acids (Part II)","link":"http:\/\/www.aklectures.com\/lecture\/fatty-acids-part-ii"},{"id":"xrn9qeVM9o4","title":"Phospholipids","link":"http:\/\/www.aklectures.com\/lecture\/phospholipids"},{"id":"c_RTc7aSFp4","title":"Glycolipids and Cholesterol","link":"http:\/\/www.aklectures.com\/lecture\/glycolipids-and-cholesterol"},{"id":"MTwUy3c5Etc","title":"Micelles and Lipid Bilayer","link":"http:\/\/www.aklectures.com\/lecture\/micelles-and-lipid-bilayer"},{"id":"KiZvvd5dhfM","title":"Liposomes (Lipid vesicles)","link":"http:\/\/www.aklectures.com\/lecture\/liposomes-lipid-vesicles"},{"id":"mkkQK6emawM","title":"Permeability of Cell Membrane","link":"http:\/\/www.aklectures.com\/lecture\/permeability-of-cell-membrane"},{"id":"AB0tlX6IUYU","title":"Integral and Peripheral Membrane Proteins","link":"http:\/\/www.aklectures.com\/lecture\/integral-and-peripheral-membrane-proteins"},{"id":"Onq25qxxsco","title":"Integral and Peripheral Membrane Proteins (Part II)","link":"http:\/\/www.aklectures.com\/lecture\/integral-and-peripheral-membrane-proteins-part-ii"},{"id":"eHEsOFGOSC4","title":"Lateral Diffusion of Lipids and Proteins","link":"http:\/\/www.aklectures.com\/lecture\/lateral-diffusion-of-lipids-and-proteins"},{"id":"ftgQ8-w8YGA","title":"Flip-Flopping and Fluid Mosaic Model","link":"http:\/\/www.aklectures.com\/lecture\/flip-flopping-and-fluid-mosaic-model"},{"id":"h7x6Ojc_6iI","title":"Asymmetry of Cell Membrane","link":"http:\/\/www.aklectures.com\/lecture\/asymmetry-of-cell-membrane"},{"id":"wnBTZ02wnAE","title":"Cholesterol and Fatty Acids Regulate Membrane Fluidity","link":"http:\/\/www.aklectures.com\/lecture\/cholesterol-and-fatty-acids-regulate-membrane-fluidity"}]
Comments
Playlists
Login to create and share playlists